We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What is Propylhexedrine?

By B. Chisholm
Updated Feb 28, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Propylhexedrine is an amphetamine-like stimulant drug that is used mainly intra-nasally, as a decongestant. It is known by various trade names around the world. Due to its stimulant properties, propylhexedrine has been used as a drug of abuse, although its abuse potential is lower than that of other amphetamines.

Due to its anorectic properties, propylhexedrine was previously available as an oral tablet used for weight loss. It has been withdrawn from the market in most countries due to the addictive properties of the drug. It is still available, however, as an inhaler in some countries.

Nasal congestion is caused by vasodilation of the blood vessels in the nose, throat and sinuses. This causes irritation and inflammation and a feeling of stuffiness, which can be as a result of allergies such as hay fever or illnesses like colds. Propylhexedrine works by causing vasoconstriction of the blood vessels and, therefore, relief from the stuffiness.

Propylhexedrine should be used only for the short term, as one of its main side effects is rhinitis medicamentosa, or rebound nasal congestion. It should not be used for more than three days in a row, as rebound nasal congestion can result five to seven days after starting use of the inhaler. Rebound nasal congestion is probably caused by a negative feedback system, which, on stopping the inhaler, causes more vasodilation and further blockage of the nasal passages. People often try to use more propylhexedrine or use it more frequently to combat the problem, which actually worsens it.

Abuse of propylhexedrine has been practiced in various ways, including inhalation, injection and oral use. Some cases of ingestion of the cotton innards of the inhaler have been reported. This is an extremely dangerous practice, as the cotton can cause gastrointestinal blockages and internal infection. In addition to these mechanical adverse effects, abuse of the drug itself has potentially dangerous effects, such as addiction, tachycardia, convulsions and serious heart problems.

The use of propylhexedrine inhalers can reduce congestion related to sinusitis, allergy or colds. Most inhalers contain menthol and lavender in combination with the drug, which enhances the decongestant effect. Inhalers should not be shared, as this can promote the spread of infection. If any adverse effects are experienced, or if there are concomitant diseases or medicines being used, advice should be sought from a doctor or pharmacist before using the product.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.