We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Are the Uses of Midazolam IV?

By Susan Abe
Updated Feb 10, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Midazolam is a powerful benzodiazepine medication usually given intravenously (IV) or as an oral syrup for children. Benzodiazepine medications, particularly those administered IV, quickly work on the brain's gamma-Aminobutyric acid neurotransmitter system to decrease anxiety and increase sedation. Among the many benzodiazepine medications, short-acting midazolam IV most effectively results in a short-term memory loss in addition to its sedative and anti-anxiety effects. Midazolam IV is thus considered an extremely effective pre-procedure medication in those instances where a patient will not be anesthetized or totally unconscious as it results in a semi-conscious state often referred to as twilight sleep. It is used primarily to treat preoperative anxiety, induce twilight sleep during medical procedures and, rarely, to cause seizure cessation in situations such as status epilepticus.

Preoperative anxiety is often treated with midazolam IV. The use of the medication in this way is particularly helpful if significant patient preparation is required prior to actual anesthetic induction and the beginning of the surgery. A patient treated with midazolam IV can be roused from light sedation to assist in transfers from the stretcher to the operating room table or to move into postural positions necessary for the procedure. When conscious, yet sedated, a patient is not as prone to anxiety reactions when medical equipment with which he is unfamiliar is introduced or applied. Further, the short-term memory loss caused by midazolam often results in a patient's complete amnesia of this preoperative even, particularly when its administration is followed by a complete anesthetic induction.

Midazolam IV is often used prior to and during diagnostic or treatment procedures where the patient will not undergo full anesthetic induction. It is used to maintain a patient in twilight sleep during potential uncomfortable procedures such as colonoscopies or upper endoscopies. The short-term amnesia prevents the patient from remembering any significant episodes of pain during the procedure and decreases his anxiety during the activity. He remains capable, however, of being aroused to consciousness in order to assist with postural changes or other actions necessary to complete the medical procedure. Midazolam IV or syrup is often used in small children to attain sedated cooperation in performing some medical tests and procedures.

Specific monitoring equipment, nursing care and medical supervision are required when using midazolam IV for preoperative anxiety, twilight sleep or epileptic seizures. This medication can cause significant respiratory depression, particularly when administered via this route. All patients treated with midazolam IV should be monitored for adequate respiratory effort and adequate oxygenation of the tissues with a pulse oximeter. Constant monitoring is required until the patient regains full consciousness.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.