We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

How Effective Is Gemcitabine for Lung Cancer?

By Lee Johnson
Updated Feb 04, 2024
Our promise to you
WiseGeek is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGeek, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Gemcitabine for lung cancer is an effective treatment when combined with cisplatin, but otherwise, it has no marked effect. Positive results for this combination qualify it only to be one of several options for the treatment of non-small cell lung cancer, as opposed to a recommended treatment. Studies have looked into the effect of gemcitabine for lung cancer when combined with cisplatin, and they have found positive results. Despite this, the drug taken on its own is not effective as a treatment, and switching cisplatin for another drug, such as carboplatin, also is ineffective.

Cancer is caused by cell division outside of the limitations normally imposed by normal cells. Drugs such as gemcitabine are classed as antimetabolites, which masquerade as ordinary substances that are part of cells and prevent them from dividing when they are brought into the cell. Cancer is caused by unneeded cell division, which forms into a tumor. When gemcitabine for lung cancer is taken, it interferes with pyrimidine to prevent the cell from dividing and increasing the size of the tumor.

Research done into the effects of gemcitabine for lung cancer indicates that it can be recommended in non-small cell lung cancer, but only when its use is combined with the use of cisplatin. Non-small cell lung cancer, which is not as quick-spreading as small cell lung cancer, is the most common variety of lung cancer. The three types of non-small cell lung cancer are adenocarcinomas, squamous cell carcinomas and large cell carcinomas. Adenocarcinomas are found on the outside of the lung, squamous cell carcinomas occur in the center of the lung, and large cell carcinomas can occur anywhere on the lung. Large cell carcinomas spread the fastest, and the tumors grow much more quickly.

Studies have shown that using gemcitabine for lung cancer with no other treatment is not effective. When combined with cisplatin, the drug has been shown to have positive effects on survival rates of patients. Other combinations, however, such as gemcitabine and carboplatin or taxane, have been shown to be ineffective as a primary treatment.

Scientists have speculated that certain molecules could be tested to indicate whether gemcitabine will be an effective treatment. If these predictors can be identified, doctors will have a much easier job when determining the recommended course of treatment for patients who have lung cancer. Gemcitabine for lung cancer in combination with cisplatin is only one of several options, but genome-based approaches might make it easier to customize the treatment and gain a better outcome.

WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Link to Sources
Discussion Comments
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.