Fitness
Fact-checked

At WiseGEEK, we're committed to delivering accurate, trustworthy information. Our expert-authored content is rigorously fact-checked and sourced from credible authorities. Discover how we uphold the highest standards in providing you with reliable knowledge.

Learn more...

What is Serrapeptase?

Donn Saylor
Donn Saylor

Serrapeptase is a proteolytic enzyme, or protease, isolated from the intestine of the silkworm. Proteases are enzymes that break down proteins, and they have been utilized for a variety of medical purposes, including the removal of damaged wound tissue and the treatment of blood clots in certain types of strokes. Serrapeptase is known by a variety of other names such as serralysin, serratiapeptase, serratia peptidase, serratio peptidase, and serrapeptidase.

Originating in the microorganism Serratia E-15 protease, serrapeptase was first isolated from the silkworm in the 1960s. It is naturally occurring in the silkworm's intestine and facilitates the dissolution of the cocoon after the worm has transformed into a moth. It was historically used as a healing agent in Germany and Asia. Today, it is produced after a process of fermentation and is widely available for human medical use.

Serrapeptase is an enzyme made in the intestine of the silkworm.
Serrapeptase is an enzyme made in the intestine of the silkworm.

Serrapeptase is thought to possess distinctive health benefits. Practitioners of alternative health and wellness cite several uses for serrapeptase. Its main draw is its anti-inflammatory properties and has been shown to reduce inflammation and ease the pain associated with arthritis and carpal tunnel syndrome. Serrapeptase also has been used to reduce blockages associated with arterial flow and helps remove plaque from the artery walls. It can also be taken as a preventative measure to ward off strokes.

Some believe that serrapeptase can reduce the swelling after dental surgery.
Some believe that serrapeptase can reduce the swelling after dental surgery.

There are other conditions that may also reap the rewards of serrapeptase. Painful swelling after dental surgery can be dramatically reduced, for example. In Japan, serrapeptase is often given to patients afflicted with chronic airway ailments as well. Additionally, it can help dissolve cysts, consuming the dead tissue until the cyst is significantly shrunken or gone completely.

Side effects of serrapeptase may include liver problems.
Side effects of serrapeptase may include liver problems.

Despite the positive benefits experienced by many who have used it, serrapeptase remains largely unstudied and should be used with caution. There have been a few minor side effects reported. Among them are minor, generalized pain, skin allergies, and pneumonitis, an inflammation of the lung tissue. In one highly publicized case, a young woman developed life-threatening liver problems after taking serrapeptase. It is not known to interfere with other medications.

Side effects of serrapeptase may include lung inflammation.
Side effects of serrapeptase may include lung inflammation.

Serrapeptase can be purchased in capsule or tablet form. While some brands claim the enzyme can be taken two or three times per day, many experts have warned against this high dosage. Until more is known about the properties and effects of serrapeptase, users should limit their intake to one capsule or tablet per day and only take it five days out of the week. And as with any medication, a doctor should be consulted before beginning a treatment regimen.

Discussion Comments

anon293719

I prefer 40,000 su every other day on an empty stomach. A high dose might have caused the appearance of fine spider veins on my legs, but they went away when the dose was decreased. It surprisingly dropped my blood pressure to a good range and surprisingly got rid of creaking of my joints -- all good.

Post your comments
Login:
Forgot password?
Register:
    • Serrapeptase is an enzyme made in the intestine of the silkworm.
      By: lily
      Serrapeptase is an enzyme made in the intestine of the silkworm.
    • Some believe that serrapeptase can reduce the swelling after dental surgery.
      By: Vladimir Melnik
      Some believe that serrapeptase can reduce the swelling after dental surgery.
    • Side effects of serrapeptase may include liver problems.
      By: joshya
      Side effects of serrapeptase may include liver problems.
    • Side effects of serrapeptase may include lung inflammation.
      By: CLIPAREA.com
      Side effects of serrapeptase may include lung inflammation.
    • Serrapeptase may be used in addition to bracing to reduce pain and inflammation caused by arthritis and carpal tunnel syndrome.
      By: waxart
      Serrapeptase may be used in addition to bracing to reduce pain and inflammation caused by arthritis and carpal tunnel syndrome.
    • Serrapeptase helps remove plaque from the artery walls. It can also be taken as a preventative measure to ward off strokes.
      By: decade3d
      Serrapeptase helps remove plaque from the artery walls. It can also be taken as a preventative measure to ward off strokes.