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What is Norethindrone?

D. Jeffress
D. Jeffress

Norethindrone is a prescription drug used to treat certain female reproductive tract disorders, including endometriosis and irregular or absent periods. It is a synthetic hormone that is similar in structure and function to the naturally produced hormone progesterone. When norethindrone is used exactly how it is prescribed by a doctor, most women see significant improvement in their symptoms in a few weeks or months. The drug can potentially cause negative side effects, but they are usually mild. It is important to keep all scheduled appointments with a doctor during the course of treatment to make sure the drug is working properly and that complications do not arise.

Like natural progesterone hormones, norethindrone helps regulate menstrual activity. It produces chemical signals that stop the production of new endometrial cells in the uterus and, in the case of endometriosis, on the ovaries, fallopian tubes, or elsewhere in the body. The sudden increase in hormones also helps jump start a regular period. As the high level of hormones tapers off over the course of a few days, a withdrawal reaction occurs in the uterus that induces menstrual bleeding.

Norethindrone  produces chemical signals that stop the production of new endometrial cells in the uterus.
Norethindrone produces chemical signals that stop the production of new endometrial cells in the uterus.

Norethindrone comes in oral tablets that are designed to be taken once a day. Patients who have abnormal menstrual bleeding or absent periods are usually instructed to begin taking the drug about 14 days before their periods would theoretically begin. A doctor may prescribe between 2.5 and 10 milligram daily doses for five to ten days. When the drug works correctly, menstrual bleeding begins sometime within the first week after treatment is stopped. Patients who suffer from endometriosis are typically given between five and 15 milligram doses to take daily for six to nine months to help prevent symptoms.

Common side effects of norethindrone include nausea and an upset stomach.
Common side effects of norethindrone include nausea and an upset stomach.

It is possible to experience side effects when taking norethindrone. Common temporary reactions include upset stomach, nausea, dizziness, and headache. Since the drug alters the balance of hormones in a woman's body, other possible complications include weight gain, tenderness and swelling in the breasts, acne, increased facial hair growth, and decreased sex drive. Rarely, the medication can cause more serious reactions, such as painful migraines, jaundice, depression, and blood pressure fluctuations.

In endometriosis, norethindrone produces chemical signals that stop the production of new endometrial cells in the uterus.
In endometriosis, norethindrone produces chemical signals that stop the production of new endometrial cells in the uterus.

It is important to report any serious or persistent side effects to a doctor right away. He or she may need to adjust the dosage amount of norethindrone or consider trying a different type of medication. Most patients who do not experience major reactions respond very well to treatment and are able to establish regular, less painful menstrual cycles.

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    • Norethindrone  produces chemical signals that stop the production of new endometrial cells in the uterus.
      By: blueringmedia
      Norethindrone produces chemical signals that stop the production of new endometrial cells in the uterus.
    • Common side effects of norethindrone include nausea and an upset stomach.
      By: ryanking999
      Common side effects of norethindrone include nausea and an upset stomach.
    • In endometriosis, norethindrone produces chemical signals that stop the production of new endometrial cells in the uterus.
      By: joshya
      In endometriosis, norethindrone produces chemical signals that stop the production of new endometrial cells in the uterus.