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What is Ceftriaxone?

Tricia Christensen
Tricia Christensen
Tricia Christensen
Tricia Christensen

Ceftriaxone is an antibiotic used in the treatment of a wide variety of medical conditions. This cephalosporin drug may not be as well known as some of its close relatives like cephalexin (Keflex®), or cefixime (Suprax), because it is usually administered by injection or intravenously (IV). It is possible for some people to use ceftriaxone injections at home, but they are more used in doctor’s offices or other health facilities, while most IV medicines are more commonly prescribed in hospitals or health clinics.

One of the most important observations about ceftriaxone is because it is a cephalosporin, people with an allergy to penicillin may also develop an allergy to it. All of the cephalosporin antibiotics carry this warning, and sensitivity to one cephalosporin may mean greater sensitivity to others. People should definitely discuss with their doctors if they’ve had an allergic reaction to penicillin or another cephalosporin in the past. Symptoms of severe allergy include hives, rash, difficulty breathing, asthmatic symptoms, and swelling of the face, lips, and tongue.

Hives may be an indication of a medication allergy.
Hives may be an indication of a medication allergy.

Along with medication sensitivities, a few medical conditions or problems may make ceftriaxone not the best choice for everyone. This drug is not recommended for people with liver, gallbladder or kidney disease. It may risk serious stomach side effects if a person has ongoing intestinal conditions like irritable bowel syndrome or Crohn’s disease. Breastfeeding women are also advised against taking this medication.

Ceftriaxone is usually administered intravenously.
Ceftriaxone is usually administered intravenously.

Where indicated, ceftriaxone can prove highly beneficial. It is one of the first drugs considered to treat certain forms of bacterial meningitis. Several injections of it can effectively cure gonorrhea. It can also be useful in treating bacterial inflammation of the heart, addressing Lyme disease, or alleviating typhoid. The medicine has numerous other uses and is effective against a variety of bacterial types.

Some medical experts believe that eating yogurt on a daily basis may help keep vaginal bacteria from multiplying during antibiotic treatment.
Some medical experts believe that eating yogurt on a daily basis may help keep vaginal bacteria from multiplying during antibiotic treatment.

When given by injection, people may receive one or two injections a day. Indications for total amount and days of use depend on the disease being treated. If the medicine is being used at home, people should remember that it generally has to be used with an additional liquid solution. People should be well trained on how to inject this medication if they will do it without medical assistance.

Ceftriaxone is one of the first drugs considered to treat certain forms of bacterial meningitis.
Ceftriaxone is one of the first drugs considered to treat certain forms of bacterial meningitis.

Like most medications, ceftriaxone has some side effects. Many of these are mild and include sweating or flushing, pain at the injection site, diarrhea, or headache. More severe side effects should be reported right away to doctors and can include stomach cramping, bloating, vomiting, chest discomfort, acid indigestion, fever, severe or bloody diarrhea, and rash. Use of antibiotics can also cause greater risk for oral or genital yeast infections; many physicians recommend adding yogurt with live active cultures to the daily diet to reduce this risk slightly.

Since ceftriaxone may be administered for only a day or two, people may forget the importance of finishing all doses of this medicine if it’s taken for several weeks’ time. It’s exceptionally important to fully complete a prescribed course of antibiotics or infection may rebound and become much harder to defeat.

Tricia Christensen
Tricia Christensen

Tricia has a Literature degree from Sonoma State University and has been a frequent WiseGEEK contributor for many years. She is especially passionate about reading and writing, although her other interests include medicine, art, film, history, politics, ethics, and religion. Tricia lives in Northern California and is currently working on her first novel.

Learn more...
Tricia Christensen
Tricia Christensen

Tricia has a Literature degree from Sonoma State University and has been a frequent WiseGEEK contributor for many years. She is especially passionate about reading and writing, although her other interests include medicine, art, film, history, politics, ethics, and religion. Tricia lives in Northern California and is currently working on her first novel.

Learn more...

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    • Hives may be an indication of a medication allergy.
      By: Jürgen Fälchle
      Hives may be an indication of a medication allergy.
    • Ceftriaxone is usually administered intravenously.
      By: Africa Studio
      Ceftriaxone is usually administered intravenously.
    • Some medical experts believe that eating yogurt on a daily basis may help keep vaginal bacteria from multiplying during antibiotic treatment.
      By: nenetus
      Some medical experts believe that eating yogurt on a daily basis may help keep vaginal bacteria from multiplying during antibiotic treatment.
    • Ceftriaxone is one of the first drugs considered to treat certain forms of bacterial meningitis.
      By: rob3000
      Ceftriaxone is one of the first drugs considered to treat certain forms of bacterial meningitis.