Health
Fact-checked

At WiseGEEK, we're committed to delivering accurate, trustworthy information. Our expert-authored content is rigorously fact-checked and sourced from credible authorities. Discover how we uphold the highest standards in providing you with reliable knowledge.

Learn more...

What is Adenoid Cystic Cancer?

A. Pasbjerg
A. Pasbjerg

Human glandular and secretory tissues can sometimes be affected by adenoid cystic cancer. This rare type of carcinoma, also known as AdCC, usually attacks the salivary glands, though it has been known to occur in other areas such as the trachea, breast tissue, and lacrimal glands. It often affects older people, but may also be diagnosed in children as well.

One of the unusual and complicating factors with adenoid cystic cancer is its tendency to spread to remote parts of the body. The original tumor may arise in the head or neck, but it often metastasizes, or spreads, to distant locations not associated with the original site. The most common area to find tumors that have spread from an AdCC tumor is the lungs. This behavior is uncommon for cancer, which often moves into the nearby lymph nodes; adenoid cystic cancer only does so in a small number of cases.

A human head with the adenoids in red and yellow.
A human head with the adenoids in red and yellow.

Adenoid cystic cancer typically has a very slow growth rate. This often leads to a relatively high survival rate in patients at first, as the cancer takes time to progress and there is a good opportunity for treatment. This type of cancer often recurs, however, and may spread aggressively; its tendency to move to different areas of the body can also make it more difficult to treat. Many patients live with the disease for a long time, but survival rates decline the longer it persists.

Cancerous cells could spread to the lymph nodes in the neck.
Cancerous cells could spread to the lymph nodes in the neck.

Due to its propensity to attack the salivary glands, adenoid cystic cancer often causes masses in the neck, mouth, or face. The tumors are initially painless, but as they grow they may cause pain and numbness. This is due to their tendency to spread along the nerve paths, putting pressure on the nerves. Depending on the location of the tumors, they may also affect nearby structures like the eyes, trachea, or larynx, which can in turn impact vision, breathing, and speech.

Adenoid cystic cancer has a propensity to attack the salivary glands.
Adenoid cystic cancer has a propensity to attack the salivary glands.

Surgery to remove the tumors is the most frequently used treatment for adenoid cystic cancer. It is important to cleanly remove all of the affected tissue; this can sometimes be difficult depending on the tumors' locations in the head and neck and because they spread out along the nerves. If surgery cannot adequately address all of the cancerous material, follow-up with radiation or neutron beam therapy will likely be necessary. Chemotherapy is less common, but may be used if the cancer metastasizes.

Discuss this Article

Post your comments
Login:
Forgot password?
Register:
    • A human head with the adenoids in red and yellow.
      By: rob3000
      A human head with the adenoids in red and yellow.
    • Cancerous cells could spread to the lymph nodes in the neck.
      By: Syda Productions
      Cancerous cells could spread to the lymph nodes in the neck.
    • Adenoid cystic cancer has a propensity to attack the salivary glands.
      By: dr_ox
      Adenoid cystic cancer has a propensity to attack the salivary glands.
    • Depending on the location of the tumors, the eyes may also be affected.
      By: Oleksii Sergieiev
      Depending on the location of the tumors, the eyes may also be affected.
    • Adenoid cystic cancer often causes masses in the neck, mouth or face.
      By: Max Tactic
      Adenoid cystic cancer often causes masses in the neck, mouth or face.